View : 37 Download: 6

Biokinetics of zinc oxide nanoparticles: toxicokinetics, biological fates, and protein interaction

Title
Biokinetics of zinc oxide nanoparticles: toxicokinetics, biological fates, and protein interaction
Authors
Choi, Soo-JinChoy, Jin-Ho
Ewha Authors
최진호
SCOPUS Author ID
최진호scopus
Issue Date
2014
Journal Title
INTERNATIONAL JOURNAL OF NANOMEDICINE
ISSN
1178-2013JCR Link
Citation
vol. 9, pp. 261 - 269
Keywords
ZnO nanoparticlesbiokineticsdistributionexcretionfateinteraction
Publisher
DOVE MEDICAL PRESS LTD
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
Biokinetic studies of zinc oxide (ZnO) nanoparticles involve systematic and quantitative analyses of absorption, distribution, metabolism, and excretion in plasma and tissues of whole animals after exposure. A full understanding of the biokinetics provides basic information about nanoparticle entry into systemic circulation, target organs of accumulation and toxicity, and elimination time, which is important for predicting the long-term toxic potential of nanoparticles. Biokinetic behaviors can be dependent on physicochemical properties, dissolution property in biological fluids, and nanoparticle-protein interaction. Moreover, the determination of biological fates of ZnO nanoparticles in the systemic circulation and tissues is critical in interpreting biokinetic behaviors and predicting toxicity potential as well as mechanism. This review focuses on physicochemical factors affecting the biokinetics of ZnO nanoparticles, in concert with understanding bioavailable fates and their interaction with proteins.
DOI
10.2147/IJN.S57920
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
Files in This Item:
001.pdf(525.93 kB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE