In this note we construct an anti-symplectic involution on the non-Kahler, symplectic 4-manifold which is constructed by Thurston and show that the quotient of the Thurston's 4-manifold is not symplectic. Also we construct a non-Kiihler, symplectic 4-manifold using the Comph's symplectic sum method and an anti-symplectic involution on the non-Kiihler, symplectic 4-manifold.