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Lessons from nature: stimuli-responsive polymers and their biomedical applications

Title
Lessons from nature: stimuli-responsive polymers and their biomedical applications
Authors
Jeong, BGutowska, A
Ewha Authors
정병문
SCOPUS Author ID
정병문scopus
Issue Date
2002
Journal Title
TRENDS IN BIOTECHNOLOGY
ISSN
0167-7799JCR Link
Citation
vol. 20, no. 7, pp. 305 - 311
Publisher
ELSEVIER SCIENCE LONDON
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
Response to stimulus is a basic process of living systems. Based on the lessons from nature, scientists have been designing useful materials that respond to external stimuli such as temperature, pH, light, electric field, chemicals and ionic strength. These responses are manifested as dramatic changes in one of the following: shape, surface characteristics, solubility, formation of an intricate molecular self-assembly or a sol-to-gel transition. Applications of stimuliresponsive, or 'smart, polymers in delivery of therapeutics, tissue engineering, bioseparations, sensors or actuators have been studied extensively and numerous papers and patents are evidence of rapid progress in this area. Understanding the structure-property relationship is essential for the further development and rational design of new functional smart materials. For example, kinetic and thermodynamic control of the coil-to-globule transition could be achieved through changes in polymer composition and topology.
DOI
10.1016/S0167-7799(02)01962-5
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자연과학대학 > 화학·나노과학전공 > Journal papers
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