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Synthesis of novel 3 '-deoxy-3 '-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents
- Title
- Synthesis of novel 3 '-deoxy-3 '-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents
- Authors
- Chun, MW; Kim, MJ; Jo, UH; Kim, JH; Kim, HD; Jeong, LS
- Ewha Authors
- 정낙신
- SCOPUS Author ID
- 정낙신
- Issue Date
- 2001
- Journal Title
- NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- ISSN
- 1525-7770
- Citation
- NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS vol. 20, no. 4-7, pp. 699 - 702
- Publisher
- MARCEL DEKKER INC
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
Proceedings Paper
- Abstract
- Based on the fact that the ring expanded 3'-C-hydroxymethyl analogue of oxetanocin A exhibited potent antiviral activity, two types of conformationally rigid 3'-C-hydroxymethyl derivatives in which 2'-hydroxyl group is linked to the 4'-position or to the 6'-position were synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose, respectively.
- DOI
- 10.1081/NCN-100002354
- Appears in Collections:
- 약학대학 > 약학과 > Journal papers
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