The effect of solvent on the alpha-effect: C=O, P=O and SO2 centers

Abstract

The alpha -effect for the reaction of a sulfonyl ester exhibits a bell-shaped dependence of the alpha -effect on solvent composition as do the corresponding reactions with a carbonyl and a phosphinyl ester, and the magnitude of the alpha -effect is found to be dependent on the magnitude of the beta (nuc) value, suggesting TS stabilization as the cause of the alpha -effect.