DSpace at EWHA: Design and syntheses of 2-oxiranecarboxylate derivatives and their hypoglycemic activities

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DC Field	Value	Language
dc.contributor.author	김화정	*
dc.date.accessioned	2016-08-27T02:08:27Z	-
dc.date.available	2016-08-27T02:08:27Z	-
dc.date.issued	2000	*
dc.identifier.issn	0385-5414	*
dc.identifier.other	OAK-420	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/215351	-
dc.description.abstract	A series of 2-oxiranecarboxylate derivatives were prepared as carnitine palmitoyl transferase I (CPT-I) inhibitors for the development of new antidiabetic agents. The syntheses and biological activities were reported. The most promising derivative (13b) showed 2.5 times more hypoglycemic activity and 2 times lower acute toxicity compared to Etomoxir ((3)).	*
dc.language	English	*
dc.publisher	PERGAMON-ELSEVIER SCIENCE LTD	*
dc.title	Design and syntheses of 2-oxiranecarboxylate derivatives and their hypoglycemic activities	*
dc.type	Article	*
dc.relation.issue	3	*
dc.relation.volume	52	*
dc.relation.index	SCI	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	1087	*
dc.relation.lastpage	+	*
dc.relation.journaltitle	HETEROCYCLES	*
dc.identifier.wosid	WOS:000086813700017	*
dc.identifier.scopusid	2-s2.0-0034162704	*
dc.author.google	Jew, S	*
dc.author.google	Kim, E	*
dc.author.google	Je, S	*
dc.author.google	Zhao, LX	*
dc.author.google	Kim, H	*
dc.author.google	Park, W	*
dc.author.google	Ko, K	*
dc.author.google	Kim, W	*
dc.author.google	Kim, HJ	*
dc.author.google	Cheong, JH	*
dc.author.google	Lee, ES	*
dc.contributor.scopusid	김화정(56670336100)	*
dc.date.modifydate	20240118124308	*