Full metadata record
DC Field | Value | Language |
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dc.contributor.advisor | 서명은 | - |
dc.contributor.author | 박미선 | - |
dc.creator | 박미선 | - |
dc.date.accessioned | 2016-08-26T10:08:39Z | - |
dc.date.available | 2016-08-26T10:08:39Z | - |
dc.date.issued | 1987 | - |
dc.identifier.other | OAK-000000015243 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/196867 | - |
dc.identifier.uri | http://dcollection.ewha.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000015243 | - |
dc.description.abstract | lH - 2 - Mercapto - 4, 5, 6, 7 - tetrahydro - 1, 3 - diazepine 과 phenacyl bromide를 반응시켜 3 - Phenyl - 5, 6, 7, 8 - tetrahydrothiazolo[3, 2-a][1, 3]diazepine을 만들고, 여기에 친전자성 시약인 phenyl isothiocyanate를 가하여 3 - Phenyl - 9 - phenyl (thiocarbamoyl) - 5, 6, 7, 8 - tetrahydrothiazolo[3, 2-a] [1, 3]diazepinium betaine을 합성하였다. 합성된 betaine에 ethyl bromoacetate, methyl bromoacetate 와 같은 α-haloester 및 chloroacetone, P-methoxyphenacyl bromide p-chlorophenacyl bromide와 같은 α-haloketone 등의 알킬화 시약을 반응시켜 고리변환 반응에 의한 새로운 biheterocyclic compound들을 합성하고, 그 이성질화에 대해 연구하였다.;3-Phenyl-5, 6, 7, 8-tetrahydrothiazolo [3,2-a][1,3] diazepine was reacted with phenyl isothiocyanate as an electrophile to form 3-phenyl-9-phenyl (thiocarbamoyl)- 5, 6, 7, 8-tetrahydrothiazolo [3, 2-a] [1,3] diazepinium betaine. New biheterocyclic compounds via ring transformation were prepared by the reaction of the above betaine with α-haloester and α-haloketone such as ethyl bromoacetate, chloroacetone, and p-methoxyphenacyl bromide. In each ring transformation reaction, two major products considered to be geometrical isomers were obtained, respectively. | - |
dc.description.tableofcontents | 목차 = ⅲ 논문개요 = ⅴ Ⅰ. 서론 = 1 Ⅱ. 명령법 및 약어 = 7 Ⅲ. 실험재료 및 방법 = 10 A. 시약 및 기기 = 10 B. 출발물질 및 티아졸로 디아제핀-베타인의 합성 = 11 1. 1H-2-Mercapto-4,5,6,7- tetrahydro-1,3-diazepine(15)의 합성 = 11 2. 3-Phenyl-5,6,7,8-tetrahydrothiazolo-[3,2-a][1,3] diazepine(16)의 합성 = 12 3. 3-Phenyl-9-phenyl(thiocarbamoyl)-5,6,7,8-tetrah-ydrothiazolo[3,2-a][1,3]-diazepinium betaine(17)의 합성 = 13 C. Ring transformation compound의 합성 = 13 Ⅳ. 결과 및 고찰 = 18 A. 3-Phenyl-9-phenyl(thiocarbamoyl)-5,6,7,8-tetrah-ydrothiazolo[3,2-a][1,3]diazepinium betaine의 합성 = 18 B. Thiazolodiazepinium betaine과 α- haloester 및 α-haloketone과의 고리변환 반응 = 21 Ⅴ. 결론 = 30 참고문헌 = 32 부록 = 35 Abstract = 43 | - |
dc.format | application/pdf | - |
dc.format.extent | 1141181 bytes | - |
dc.language | kor | - |
dc.publisher | 이화여자대학교 대학원 | - |
dc.subject | 티아졸로 디아제핀 | - |
dc.subject | 베타인 | - |
dc.subject | 고리변환 | - |
dc.title | 티아졸로 디아제핀-베타인의 고리변환반응 | - |
dc.type | Master's Thesis | - |
dc.title.translated | Ring transformation reaction of Thiazolodiazelpinium betaine | - |
dc.format.page | 50 p. | - |
dc.identifier.thesisdegree | Master | - |
dc.identifier.major | 대학원 화학과 | - |
dc.date.awarded | 1987. 8 | - |