Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 한용봉 | - |
dc.creator | 한용봉 | - |
dc.date.accessioned | 2016-08-26T12:08:02Z | - |
dc.date.available | 2016-08-26T12:08:02Z | - |
dc.date.issued | 1973 | - |
dc.identifier.other | OAK-000000000022 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/191121 | - |
dc.identifier.uri | http://dcollection.ewha.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000000022 | - |
dc.description.abstract | Three antimicrobial alkaloids were isolated from Veratrum grandiflorum (Maxim) Loes. fil. and identified as veratramine, jervine and pseudojervine. Veratrobasine, isorubijervine, protoveratrine A and B were also detected by TLC, out of which protoveratrine A and B exhibited no antimicrobial action. Of several alkaloids tested, only jerveratrum alkaloids exhibited antimicrobial action ; jervine, pseudojervine, veratrobasine, isorubijervine and veratramine in decreasing order, were effective against Pityrosporum ovale and pseudojervine, jervine, veratramine, veratrobasine and isorubijervine against Trichophyton mentagrophytes. These results and together with the fact that solanidine is inactive against fungi suggest that oxigenation at C-11 for C-nor D-homo steroidal alkaloids and at C-18 for normal steroidal alkaloids plays an important role in activity. | - |
dc.description.tableofcontents | Ⅰ. 緖論 ------------------------------------------------------------- 1 Ⅱ. 實驗 ------------------------------------------------------------- 5 1. 侑效成分의 抽出 -------------------------------------------------- 5 2. 微生物實驗 ------------------------------------------------------- 7 1) 材料 및 方法 ---------------------------------------------------- 7 a) 材料 ----------------------------------------------------------- 7 b) 實驗方法 ------------------------------------------------------- 8 2) Crude Fraction에 對한 抗菌作用 ---------------------------------- 8 3) Crude Alkaloid에 對한 抗菌作用 ---------------------------------- 9 4) 數種 Veratrum Alkaloid의 抗菌作用 ------------------------------- 10 Ⅲ. 考察 ------------------------------------------------------------- 12 Ⅳ. 結論 ------------------------------------------------------------- 16 參考文獻 ------------------------------------------------------------- 17 Abstract ------------------------------------------------------------- 20 | - |
dc.format | application/pdf | - |
dc.format.extent | 704194 bytes | - |
dc.language | kor | - |
dc.publisher | 이화여자대학교 대학원 | - |
dc.title | 여로 알카로이드 항균작용에 관한 연구 | - |
dc.type | Doctoral Thesis | - |
dc.identifier.thesisdegree | Doctor | - |
dc.identifier.major | 대학원 약학과 | - |
dc.date.awarded | 1973. 2 | - |