향유의 Flavonoid 成分 硏究

Abstract

향유 (Elscholtzia Ciliata Hylander = Elscholtzia Patrini Garcke)는 꿀풀과 (Labiatae)에 속하는 1년생 草本으로 漢方에서는 發汗, 解熱, 利尿藥으로 쓰이고 있다. 韓國産 야생향유 全草를 MeOH로 추출한 다음 Hexane, CHcl_(3), EtOAc BuOH 순으로 분획하여 그중 EtOAc 분획을 CHcl_(3) : MeOH : H_(2)O = 25 : 6 : 0.7로 Silicagel Column Chromatography하여 4가지 새로운 물질을 분리하였고 그중 Compound Ⅳ의 구조를 동정하였다.;Elscholtzia Ciliata(Labiatae) is found in every parts of korea. The entire plant is useful in preventing beri-beri and is recommended in treating abdominal pains, kidney trouble and cholerine. Reported constituents are only essential oils with elscholtzia ketone. In a course of the work on flavonoid constituents, linarin was isolated from the ethylacetate soluble fraction together with apigenin, apigenin-7-glucoside and luteolin-7-glucoside. The structure was characterized by spectral analysis of the glycoside and its aglycone obtained by acid hydrolysis.