DSpace at EWHA: Advances and resistance adaptation in BTK-targeted therapy for B-cell malignancies

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DC Field	Value	Language
dc.contributor.author	황인아	*
dc.date.accessioned	2026-03-23T16:30:02Z	-
dc.date.available	2026-03-23T16:30:02Z	-
dc.date.issued	2026	*
dc.identifier.issn	1368-7646	*
dc.identifier.issn	1532-2084	*
dc.identifier.other	OAK-39128	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/274598	-
dc.description.abstract	Bruton's tyrosine kinase (BTK) is a key signaling component downstream of the B-cell receptor (BCR) and plays an essential role in the survival and proliferation of multiple B-cell malignancies, including chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), and Waldenstro & uml;m macroglobulinemia (WM). BTK inhibitors (BTKi) have demonstrated substantial clinical benefit and are now widely incorporated into frontline treatment strategies. However, the long-term effectiveness of BTKi is frequently limited by the emergence of both intrinsic	*
dc.language	English	*
dc.publisher	CHURCHILL LIVINGSTONE	*
dc.subject	Bruton's tyrosine kinase	*
dc.subject	BTK inhibitors	*
dc.subject	B -cell malignancies	*
dc.subject	BTK inhibitor resistance	*
dc.title	Advances and resistance adaptation in BTK-targeted therapy for B-cell malignancies	*
dc.type	Article	*
dc.relation.volume	86	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.journaltitle	DRUG RESISTANCE UPDATES	*
dc.identifier.doi	10.1016/j.drup.2026.101383	*
dc.identifier.wosid	WOS:001708829900001	*
dc.author.google	Yang, Sieun	*
dc.author.google	Oh, Jihye	*
dc.author.google	Hwang, Soo-Yeon	*
dc.author.google	Paik, Jihye	*
dc.author.google	Hwang, Inah	*
dc.contributor.scopusid	황인아(25121272200)	*
dc.date.modifydate	20260813164844	*