Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서지현 | * |
dc.date.accessioned | 2024-02-06T16:31:11Z | - |
dc.date.available | 2024-02-06T16:31:11Z | - |
dc.date.issued | 2024 | * |
dc.identifier.issn | 2373-8057 | * |
dc.identifier.other | OAK-34558 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/267022 | - |
dc.description.abstract | We aimed to investigate the association of various mental illnesses, including depression, bipolar disorder, schizophrenia, insomnia, and anxiety, with the risk of early-onset Parkinson’s disease (EOPD) (age <50 years) and compare it with that of late-onset PD (LOPD) (age ≥50 years). This nationwide cohort study enrolled 9,920,522 people who underwent a national health screening examination in 2009, and followed up until 31 December 2018. There was a significantly increased risk of EOPD and LOPD in individuals with mental illness, and EOPD showed a stronger association than LOPD (EOPD, hazard ratio (HR) = 3.11, 95% CI: 2.61‒3.72; LOPD, HR = 1.70, 95% CI: 1.66‒1.74; p for interaction <0.0001). Our results suggest that people with mental illnesses aged < 50 years are at a higher risk of PD than those aged ≥50 years. Future studies are warranted to elucidate the pathomechanism of EOPD in relation to mental illness. © 2024, The Author(s). | * |
dc.language | English | * |
dc.publisher | Nature Research | * |
dc.title | Different risks of early-onset and late-onset Parkinson disease in individuals with mental illness | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 10 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | npj Parkinson's Disease | * |
dc.identifier.doi | 10.1038/s41531-023-00621-x | * |
dc.identifier.wosid | WOS:001139057800002 | * |
dc.identifier.scopusid | 2-s2.0-85181970042 | * |
dc.author.google | Yoon | * |
dc.author.google | Seo Yeon | * |
dc.author.google | Lee | * |
dc.author.google | Sang Chul | * |
dc.author.google | Suh | * |
dc.author.google | Jee Hyun | * |
dc.author.google | Yang | * |
dc.author.google | Seung Nam | * |
dc.author.google | Han | * |
dc.author.google | Kyungdo | * |
dc.author.google | Kim | * |
dc.author.google | Yong Wook | * |
dc.contributor.scopusid | 서지현(57192986130) | * |
dc.date.modifydate | 20240502145036 | * |