View : 243 Download: 0
Association between periodontal disease status and risk of atrial fibrillation: a nationwide population-based cohort study
- Title
- Association between periodontal disease status and risk of atrial fibrillation: a nationwide population-based cohort study
- Authors
- Park; Jung-Hyun; Lee; Hyungwoo; Kim; Jin-Woo; Song; Tae-Jin
- Ewha Authors
- 송태진; 김진우; 박정현; 이형우
- SCOPUS Author ID
- 송태진; 김진우; 박정현; 이형우
- Issue Date
- 2023
- Journal Title
- BMC Oral Health
- ISSN
- 1472-6831
- Citation
- BMC Oral Health vol. 23, no. 1
- Keywords
- Atrial fibrillation; Oral health; Periodontal disease; Periodontitis
- Publisher
- BioMed Central Ltd
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Background: Periodontal disease can activate an immune process linked to systemic diseases, including atrial fibrillation. However, the relationship between periodontal disease and atrial fibrillation remains unclear. Aim: This study aimed to investigate whether changes in periodontal disease status are associated with the risk of atrial fibrillation. Methods: Using the National Health Insurance Database Korea, participants who underwent the first oral health examination in 2003 and a second examination in 2005–2006 without a history of atrial fibrillation were included. Participants were grouped according to changes in periodontal disease status during two oral examinations: periodontal disease-free, periodontal disease-recovered, periodontal disease-developed, and periodontal disease-chronic. The outcome was the incidence of atrial fibrillation. Results: The study included 1,254,515 participants, with a median follow-up of 14.3 years and 25,402 (2.02%) cases of atrial fibrillation occurred. During follow-up, the risk of atrial fibrillation was highest in the periodontal disease-chronic group, followed by the periodontal disease-developed, periodontal disease-recovered, and periodontal disease-free groups (p for trend < 0.001). Moreover, recovery from periodontal disease was associated with a reduced risk of atrial fibrillation compared to a chronic periodontal disease status (Hazard ratio: 0.97, 95% Confidence interval: 0.94—0.99, p = 0.045). The development of periodontal disease was associated with an increased risk of atrial fibrillation compared to being periodontal disease-free (Hazard ratio: 1.04, 95% Confidence interval: 1.01—1.08, p = 0.035). Conclusion: Our findings suggest that changes in periodontal disease status impact the risk of atrial fibrillation. Management of periodontal disease may help prevent atrial fibrillation. © 2023, The Author(s).
- DOI
- 10.1186/s12903-023-03165-x
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML