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Clinical manifestations and perinatal outcomes of pregnant women with COVID-19: a systematic review and meta-analysis
- Title
- Clinical manifestations and perinatal outcomes of pregnant women with COVID-19: a systematic review and meta-analysis
- Authors
- Yee, Jeong; Kim, Woorim; Han, Ji Min; Yoon, Ha Young; Lee, Nari; Lee, Kyung Eun; Gwak, Hye Sun
- Ewha Authors
- 곽혜선
- Issue Date
- 2020
- Journal Title
- SCIENTIFIC REPORTS
- ISSN
- 2045-2322
- Citation
- SCIENTIFIC REPORTS vol. 10, no. 1
- Publisher
- NATURE RESEARCH
- Indexed
- SCIE; SCOPUS
- Document Type
- Review
- Abstract
- This systematic review and meta-analysis aimed to evaluate the impact of COVID-19 on pregnant women. We searched for qualified studies in PubMed, Embase, and Web of Science. The clinical characteristics of pregnant women with COVID-19 and their infants were reported as means and proportions with 95% confidence interval. Eleven studies involving with 9032 pregnant women with COVID-19 and 338 infants were included in the meta-analysis. Pregnant women with COVID-19 have relatively mild symptoms. However, abnormal proportions of laboratory parameters were similar or even increased, compared to general population. Around 30% of pregnant women with COVID-19 experienced preterm delivery, whereas the mean birth weight was 2855.9 g. Fetal death and detection of SARS-CoV-2 were observed in about 2%, whereas neonatal death was found to be 0.4%. In conclusion, the current review will serve as an ideal basis for future considerations in the treatment and management of COVID-19 in pregnant women.
- DOI
- 10.1038/s41598-020-75096-4
- Appears in Collections:
- 약학대학 > 약학과 > Journal papers
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