DSpace at EWHA: Monitoring mitochondrial nitroreductase activity in tumors and a hind-limb model of ischemia in mice using a novel activatable NIR fluorescent probe

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DSpace at EWHA자연과학대학 화학·나노과학전공 Journal papers

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DC Field	Value	Language
dc.contributor.author	윤주영	*
dc.date.accessioned	2022-10-27T16:31:13Z	-
dc.date.available	2022-10-27T16:31:13Z	-
dc.date.issued	2022	*
dc.identifier.issn	1359-7345	*
dc.identifier.issn	1364-548X	*
dc.identifier.other	OAK-32351	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/262665	-
dc.description.abstract	We report a mitochondria-targeted nitroreductase (NTR)-activated near-infrared fluorescent probe: CS-NO2. Overexpressed NTR in mitochondria was measured with high sensitivity. More importantly, the probe CS-NO2 successfully monitored NTR activity in solid tumors and a hind-limb model of ischemia in mice. This novel finding indicates the promising function of our probe for the diagnosis of solid tumors and hypoxia-associated diseases.	*
dc.language	English	*
dc.publisher	ROYAL SOC CHEMISTRY	*
dc.title	Monitoring mitochondrial nitroreductase activity in tumors and a hind-limb model of ischemia in mice using a novel activatable NIR fluorescent probe	*
dc.type	Article	*
dc.relation.issue	81	*
dc.relation.volume	58	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	11438	*
dc.relation.lastpage	11441	*
dc.relation.journaltitle	CHEMICAL COMMUNICATIONS	*
dc.identifier.doi	10.1039/d2cc04112j	*
dc.identifier.wosid	WOS:000858479500001	*
dc.author.google	Liu, Xiaosheng	*
dc.author.google	Zeng, Shuang	*
dc.author.google	Zhang, Ming	*
dc.author.google	Jiang, Maojun	*
dc.author.google	Kafuti, Yves S.	*
dc.author.google	Shangguan, Pingping	*
dc.author.google	Yu, Yichu	*
dc.author.google	Chen, Qixian	*
dc.author.google	Wang, Jingyun	*
dc.author.google	Peng, Xiaojun	*
dc.author.google	Yoon, Juyoung	*
dc.author.google	Li, Haidong	*
dc.contributor.scopusid	윤주영(7403587371)	*
dc.date.modifydate	20240118162450	*