Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 송승환 | * |
dc.date.accessioned | 2022-10-27T16:31:04Z | - |
dc.date.available | 2022-10-27T16:31:04Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 0263-6352 | * |
dc.identifier.issn | 1473-5598 | * |
dc.identifier.other | OAK-32393 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262625 | - |
dc.description.abstract | Objectives: Hypertensive living donors are potential candidates to expand the kidney donor pool. However, the impact of donor hypertension on graft survival and function remains to be clarified. Methods: We analyzed 3907 kidney transplant recipients registered in a nationwide prospective cohort from 2014 to 2018. Patients were divided by donor types and the presence of donor hypertension. The primary and secondary outcome was the occurrence of death-censored graft failure and renal allograft function, respectively. Results: The prevalence of hypertension was 9.4% (258/2740) and 19.9% (232/1167) in living and deceased donors, respectively. During a median follow-up of 21.8 months, death-censored graft survival rate was significantly worse in recipients of hypertensive living donors than in those of normotensive living donors (P = 0.008). In multivariable analysis, recipients of hypertensive living donors had a significantly increased risk of graft loss (adjusted hazard ratio 2.91; P = 0.009). The risk of allograft loss was not different between recipients of hypertensive living and normotensive deceased donors. Propensity score-matched analyses had consistent worse graft survival rate in recipients of hypertensive living donors compared to those of normotensive living donors (P = 0.027), while it was not different between recipients of hypertensive living and normotensive deceased donors. Hypertension in living donors had a significant negative impact on one-year graft function (adjusted unstandardized beta -3.64; P = 0.011). Conclusions: Hypertensive living donor recipients have significantly higher risks of renal allograft loss than normotensive living donor recipients, and showed similar outcomes compared to recipients of normotensive deceased donors. | * |
dc.language | English | * |
dc.publisher | LIPPINCOTT WILLIAMS & | * |
dc.publisher | WILKINS | * |
dc.subject | donor hypertension | * |
dc.subject | kidney transplantation | * |
dc.subject | renal allograft function | * |
dc.subject | renal allograft survival | * |
dc.title | Impact of donor hypertension on graft survival and function in living and deceased donor kidney transplantation: a nationwide prospective cohort study | * |
dc.type | Article | * |
dc.relation.issue | 11 | * |
dc.relation.volume | 40 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 2200 | * |
dc.relation.lastpage | 2209 | * |
dc.relation.journaltitle | JOURNAL OF HYPERTENSION | * |
dc.identifier.doi | 10.1097/HJH.0000000000003246 | * |
dc.identifier.wosid | WOS:000864723600014 | * |
dc.identifier.scopusid | 2-s2.0-85139377780 | * |
dc.author.google | Lee, Yu Ho | * |
dc.author.google | Kim, Jin Sug | * |
dc.author.google | Song, Sang Heon | * |
dc.author.google | Song, Seung Hwan | * |
dc.author.google | Shin, Ho Sik | * |
dc.author.google | Yang, Jaeseok | * |
dc.author.google | Ahn, Curie | * |
dc.author.google | Jeong, Kyung Hwan | * |
dc.author.google | Hwang, Hyeon Seok|Kotry Study Grp | * |
dc.contributor.scopusid | 송승환(57226657760) | * |
dc.date.modifydate | 20240315141121 | * |