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dc.contributor.author송태진*
dc.contributor.author장윤경*
dc.date.accessioned2022-08-02T16:30:39Z-
dc.date.available2022-08-02T16:30:39Z-
dc.date.issued2022*
dc.identifier.issn1876-0341*
dc.identifier.issn1876-035X*
dc.identifier.otherOAK-31834*
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/261638-
dc.description.abstractBackground: Triglyceride-glucose (TyG) index is a simple and reliable surrogate marker for insulin re-sistance. Epidemiology studies have shown that insulin resistance is a risk factor for various infectious diseases. We evaluated the prognostic value of TyG index measured before the COVID-19 infection in COVID-19 infected patients. Methods: From a nationwide COVID-19 cohort dataset in Korea, we included COVID-19 patients diagnosed between Jan and Jun 2020. Based on the nationwide health screening data between 2015 and 2018, TyG index was calculated as ln [triglyceride (mg/dL) x fasting glucose level (mg/dL)/2]. Primary outcome is development of severe complications of COVID-19 defined as composite of mechanical ventilation, intensive care unit care, high-flow oxygen therapy, and mortality within two months after the diagnosis of COVID-19.Results: This study included 3887 patients with COVID-19 confirmed by reverse transcription polymerase chain reaction. Mean +/- standard deviation of TyG index was 8.54 +/- 0.61. Severe complications of COVID-19 were noted in 289 (7.4 4%) patients. In the multivariate logistic regression, TyG index was positively asso-ciated with severe complications of COVID-19 (adjusted odds ratio: 1.42, 95% confidence interval [1.12-1.79]).Conclusions: In COVID-19 infected patients, high TyG index was associated with increased risk for severe complications. TyG index might be useful predictor for the severity of COVID-19 infection.(c) 2022 Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. CC_BY_NC_ND_4.0*
dc.languageEnglish*
dc.publisherELSEVIER SCIENCE LONDON*
dc.subjectCOVID-19*
dc.subjectInsulin resistance*
dc.subjectTriglyceride-glucose index*
dc.subjectGlucose*
dc.titleAssociation of triglyceride-glucose index with prognosis of COVID-19: A population-based study*
dc.typeArticle*
dc.relation.issue8*
dc.relation.volume15*
dc.relation.indexSCIE*
dc.relation.indexSCOPUS*
dc.relation.startpage837*
dc.relation.lastpage844*
dc.relation.journaltitleJOURNAL OF INFECTION AND PUBLIC HEALTH*
dc.identifier.doi10.1016/j.jiph.2022.06.014*
dc.identifier.wosidWOS:000822548400001*
dc.identifier.scopusid2-s2.0-85133264182*
dc.author.googleChang, Yoonkyung*
dc.author.googleJeon, Jimin*
dc.author.googleSong, Tae-Jin*
dc.author.googleKim, Jinkwon*
dc.contributor.scopusid송태진(55507164200;57222053351)-
dc.contributor.scopusid장윤경(56525550900)-
dc.date.modifydate20221116112629*
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의과대학 > 의학과 > Journal papers
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