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An Interactive Online App for Predicting Diabetes via Machine Learning from Environment-Polluting Chemical Exposure Data

Title
An Interactive Online App for Predicting Diabetes via Machine Learning from Environment-Polluting Chemical Exposure Data
Authors
Oh R.Lee H.K.Pak Y.K.Oh M.-S.
Ewha Authors
오만숙
SCOPUS Author ID
오만숙scopus
Issue Date
2022
Journal Title
International Journal of Environmental Research and Public Health
ISSN
1661-7827JCR Link
Citation
International Journal of Environmental Research and Public Health vol. 19, no. 10
Keywords
Bayesian networkdiabetes mellitusenvironmental pollutantsglucose intolerancemachine learning
Publisher
MDPI
Indexed
SCIE; SSCI; SCOPUS WOS scopus
Document Type
Article
Abstract
The early prediction and identification of risk factors for diabetes may prevent or delay diabetes progression. In this study, we developed an interactive online application that provides the predictive probabilities of prediabetes and diabetes in 4 years based on a Bayesian network (BN) classifier, which is an interpretable machine learning technique. The BN was trained using a dataset from the Ansung cohort of the Korean Genome and Epidemiological Study (KoGES) in 2008, with a follow-up in 2012. The dataset contained not only traditional risk factors (current diabetes status, sex, age, etc.) for future diabetes, but it also contained serum biomarkers, which quantified the individual level of exposure to environment-polluting chemicals (EPC). Based on accuracy and the area under the curve (AUC), a tree-augmented BN with 11 variables derived from feature selection was used as our prediction model. The online application that implemented our BN prediction system provided a tool that performs customized diabetes prediction and allows users to simulate the effects of controlling risk factors for the future development of diabetes. The prediction results of our method demonstrated that the EPC biomarkers had interactive effects on diabetes progression and that the use of the EPC biomarkers contributed to a substantial improvement in prediction performance. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
DOI
10.3390/ijerph19105800
Appears in Collections:
자연과학대학 > 통계학전공 > Journal papers
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