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Prospects for Protective Potential of Moringa oleifera against Kidney Diseases

Title
Prospects for Protective Potential of Moringa oleifera against Kidney Diseases
Authors
Akter, TanzinaRahman, Md AtikurMoni, AkhiApu, Md. Aminul IslamFariha, AtqiyaHannan, Md. AbdulUddin, Md Jamal
Ewha Authors
Md Jamal Uddin
SCOPUS Author ID
Md Jamal Uddinscopus
Issue Date
2021
Journal Title
PLANTS-BASEL
ISSN
2223-7747JCR Link
Citation
PLANTS-BASEL vol. 10, no. 12
Keywords
Moringa oleiferaantioxidantanti-agingfibrosisinflammationkidney disease
Publisher
MDPI
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Kidney diseases are regarded as one of the major public health issues in the world. The objectives of this study were: (i) to investigate the causative factors involved in kidney disease and the therapeutic aspects of Moringa oleifera, as well as (ii) the effectiveness of M. oleifera in the anti-inflammation and antioxidant processes of the kidney while minimizing all potential side effects. In addition, we proposed a hypothesis to improve M. oleifera based drug development. This study was updated by searching the key words M. oleifera on kidney diseases and M. oleifera on oxidative stress, inflammation, and fibrosis in online research databases such as PubMed and Google Scholar. The following validation checking and scrutiny analysis of the recently published articles were used to explore this study. The recent existing research has found that M. oleifera has a plethora of health benefits. Individual medicinal properties of M. oleifera leaf extract, seed powder, stem extract, and the whole extract (ethanol/methanol) can up-increase the activity of antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH), while decreasing the activity of inflammatory cytokines such as TNF-alpha, IL-1 beta, IL-6, and COX-2. In our study, we have investigated the properties of this plant against kidney diseases based on existing knowledge with an updated review of literature. Considering the effectiveness of M. oleifera, this study would be useful for further research into the pharmacological potential and therapeutic insights of M. oleifera, as well as prospects of Moringa-based effective medicine development for human benefits.
DOI
10.3390/plants10122818
Appears in Collections:
연구기관 > 약학연구소 > Journal papers
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