View : 14 Download: 0

Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy

Title
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Authors
Pham T.C.Nguyen V.-N.Choi Y.Lee S.Yoon J.
Ewha Authors
윤주영Nguyen Van Nghia
SCOPUS Author ID
윤주영scopus; Nguyen Van Nghiascopus
Issue Date
2021
Journal Title
Chemical Reviews
ISSN
0009-2665JCR Link
Citation
Chemical Reviews vol. 121, no. 21, pp. 13454 - 13619
Publisher
American Chemical Society
Indexed
SCIE; SCOPUS scopus
Document Type
Review
Abstract
This review presents a robust strategy to design photosensitizers (PSs) for various species. Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the use of light combined with a light-activated chemical, referred to as a PS. Attractively, PDT is one of the alternatives to conventional cancer treatment due to its noninvasive nature, high cure rates, and low side effects. PSs play an important factor in photoinduced reactive oxygen species (ROS) generation. Although the concept of photosensitizer-based photodynamic therapy has been widely adopted for clinical trials and bioimaging, until now, to our surprise, there has been no relevant review article on rational designs of organic PSs for PDT. Furthermore, most of published review articles in PDT focused on nanomaterials and nanotechnology based on traditional PSs. Therefore, this review aimed at reporting recent strategies to develop innovative organic photosensitizers for enhanced photodynamic therapy, with each example described in detail instead of providing only a general overview, as is typically done in previous reviews of PDT, to provide intuitive, vivid, and specific insights to the readers. © 2021 American Chemical Society.
DOI
10.1021/acs.chemrev.1c00381
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE