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Identification of Cardiovascular Risk Factors in Obese Adolescents With Metabolic Syndrome

Title
Identification of Cardiovascular Risk Factors in Obese Adolescents With Metabolic Syndrome
Authors
Lee, Jung WonHong, Young MiKim, Hae Soon
Ewha Authors
홍영미김혜순이정원
SCOPUS Author ID
홍영미scopus; 김혜순scopus; 이정원scopus
Issue Date
2021
Journal Title
FRONTIERS IN PEDIATRICS
ISSN
2296-2360JCR Link
Citation
FRONTIERS IN PEDIATRICS vol. 9
Keywords
metabolic syndromevisceral obesityleft ventricular mass indexvisceral fat thicknesscardiovascular disease
Publisher
FRONTIERS MEDIA SA
Indexed
SCIE; SCOPUS WOS
Document Type
Article
Abstract
Objective: There are studies that show different associations between metabolic syndrome (MS) and cardiovascular disease in adolescent. This study is aimed to identify probable cardio-vascular risk factors in obese adolescents with MS.</p> Methods: Sixty-five obese adolescents with a body mass index (BMI) > 95 percentile were enrolled and divided into two groups with MS or without MS. Left ventricular mass (LVM), left ventricular mass index, ejection fraction, epicardial fat thickness, visceral fat thickness (VFT) and carotid intima-media thickness were measured. Anthropometric and blood chemistry parameters were estimated. Above parameters were compared based on presence or absence of MS.</p> Results: The prevalence of MS was 23.1% in obese adolescents. LVM showed significant correlation with body mass index (BMI), hip circumference (HC), fat mass, total cholesterol (TC), LDL-cholesterol (LDL-C) and waist circumference (WC). VFT significantly correlated with WC, BMI, hip circumflex (HC), obesity index (OI), fat %, fat mass, insulin, TC, LDL-C, insulin, triglyceride (TG), glucose, homeostatic model assessment for insulin resistance (HOMA-IR) and leptin.</p> Conclusions: Screening for the MS in overweight adolescents may help to predict risk of future cardiovascular disease. These data suggest that LVMI and VFT are significant parameters for predicting cardiovascular disease risk in obese adolescents.</p>
DOI
10.3389/fped.2021.745805
Appears in Collections:
의과대학 > 의학과 > Journal papers
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