View : 18 Download: 0

On principal graphical models with application to gene network

Title
On principal graphical models with application to gene network
Authors
Kim K.
Ewha Authors
김경원
Issue Date
2022
Journal Title
Computational Statistics and Data Analysis
ISSN
0167-9473JCR Link
Citation
Computational Statistics and Data Analysis vol. 166
Keywords
Conjoined conditional covariance operatorReproducing Kernel Hilbert spaceSliced average variance estimationSliced inverse regressionStatistical graphical model
Publisher
Elsevier B.V.
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
The principal graphical model is introduced by incorporating the ideas from the linear sufficient dimension reduction (SDR) methods such as the sliced inverse regression and sliced average variance estimation to a nonparametric graphical model. A nonparametric graphical model is a widely used method to investigate undirected graphs. However, when the number of nodes is large, a nonparametric graphical model suffers from the ‘curse of dimensionality’ because they contain intrinsic high dimensional kernels. The parametric graphical models such as the Gaussian or copula Gaussian graphical models are also well known for their intuitive structure and interpretability. However, they hinge on strong parametric model assumptions. The principal graphical model applies well-known linear SDR techniques to the nonparametric graphical models to enhance performance in high dimensional networks, avoid model assumptions, and maintain interpretability. We use components of linear SDR as modules and implement them in the (p2) pairs of variables in the network to evaluate conditional independence. In the numerical experiment, our methods have competitive accuracy in both low and high-dimensional settings. Our methods are applied to the DREAM 4 challenge gene network dataset and they work well in high dimensional settings with a limited number of observations. © 2021 Elsevier B.V.
DOI
10.1016/j.csda.2021.107344
Appears in Collections:
자연과학대학 > 통계학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE