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공과대학
화공신소재공학과
Journal papers
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Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft
Title
Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft
Authors
Song Y.
;
Joo K.
;
II
;
Seo J.H.
Ewha Authors
주계일
SCOPUS Author ID
주계일
Issue Date
2021
Journal Title
Biotechnology and Bioprocess Engineering
ISSN
1226-8372
Citation
Biotechnology and Bioprocess Engineering vol. 26, no. 2, pp. 201 - 207
Keywords
bone graft
;
composite scaffold
;
hydroxyapatite
;
levan
;
sintering
Publisher
Korean Society for Biotechnology and Bioengineering
Indexed
SCIE; SCOPUS; KCI
Document Type
Article
Abstract
Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in load-bearing applications. Here, we developed mechanically reinforced composite scaffold containing adhesive levan as a binder for sintered hydroxyapatite (sHAp) and then examined the mechanical and thermal properties of the composite scaffold. We found that sHAp-levan composite scaffold exhibited remarkably enhanced mechanical strength, which is similar to that of polymethyl methacrylate (PMMA) bone cement. This composite scaffold can be utilized as a promising bone graft for bone regeneration and tissue engineering. © 2021, The Korean Society for Biotechnology and Bioengineering and Springer.
DOI
10.1007/s12257-020-0094-6
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