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Imaging of intracellular singlet oxygen with bright BODIPY dyes

Title
Imaging of intracellular singlet oxygen with bright BODIPY dyes
Authors
Kaya S.Ismaiel Y.A.Kwon N.Kim G.Bila J.L.Yoon J.Seven O.Akkaya E.U.
Ewha Authors
윤주영
SCOPUS Author ID
윤주영scopus
Issue Date
2021
Journal Title
Dyes and Pigments
ISSN
0143-7208JCR Link
Citation
Dyes and Pigments vol. 188
Keywords
BodipyFluorescent probePhotodynamic therapyReactive oxygen speciesSinglet oxygen probe
Publisher
Elsevier Ltd
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Singlet oxygen is a cytotoxic reactive species which is involved in the photodynamic therapy of cancer. It is also known to be produced endogenously in most eukaryotic cells and implicated in many biochemical processes, including apoptotic response. We now report that Bodipy based fluorescent dyes with singlet oxygen reactive modules, signal the intracellular generation of singlet oxygen through photosensitization. We believe long wavelength probes of singlet oxygen, based on this approach will be highly valuable. © 2021 Elsevier Ltd
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DOI
10.1016/j.dyepig.2021.109158
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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