Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서은경 | * |
dc.contributor.author | 임경민 | * |
dc.contributor.author | 남상집 | * |
dc.contributor.author | 김민정 | * |
dc.date.accessioned | 2021-01-14T16:30:12Z | - |
dc.date.available | 2021-01-14T16:30:12Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 1420-3049 | * |
dc.identifier.other | OAK-28602 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/255933 | - |
dc.description.abstract | Lycii Fructus is a traditional medicine used to prevent liver and kidney diseases, which commonly derives from Lycium chinense and Lycium barbarum. Here, the extracts and ethyl acetate-soluble fractions of L. chinense fruits exhibited better hepatoprotective effects than those of L. barbarum, which was likely due to differences in their composition. Therefore, GC-MS and HPLC analyses were conducted to characterize the metabolite differences between L. chinense and L. barbarum. Based on amino acid (AA) and phenolic acid (PA) profiling, 24 AAs and 9 PAs were identified in the two species. Moreover, each species exhibited unique and readily distinguishable AA and PA star graphic patterns. HPLC analysis elucidated composition differences between the ethyl acetate-soluble layers of the two compounds. Further, NMR analysis identified their chemical structures as 4-(2-formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl)butanoic acid and p-coumaric acid. The higher content of 4-(2-formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl)butanoic acid was detected in L. chinense, whereas the content of p-coumaric acid was higher in L. barbarum. Therefore, the differences in the relative contents of these two secondary metabolites in the ethyl acetate-soluble layer of Lycii Fructus could be a good marker to discriminate between L. chinense and L. barbarum. | * |
dc.language | English | * |
dc.publisher | NLM (Medline) | * |
dc.subject | gas chromatography-mass spectrometry | * |
dc.subject | Lycium barbarum | * |
dc.subject | Lycium chinense | * |
dc.subject | star pattern recognition analysis | * |
dc.title | Discrimination of Lycium chinense and L. barbarum Based on Metabolite Analysis and Hepatoprotective Activity | * |
dc.type | Article | * |
dc.relation.issue | 24 | * |
dc.relation.volume | 25 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Molecules (Basel, Switzerland) | * |
dc.identifier.doi | 10.3390/molecules25245835 | * |
dc.identifier.wosid | WOS:000603343200001 | * |
dc.identifier.scopusid | 2-s2.0-85098532519 | * |
dc.author.google | Ryu M.-J. | * |
dc.author.google | Kim M. | * |
dc.author.google | Ji M. | * |
dc.author.google | Lee C. | * |
dc.author.google | Yang I. | * |
dc.author.google | Hong S.-B. | * |
dc.author.google | Chin J. | * |
dc.author.google | Seo E.K. | * |
dc.author.google | Paik M.-J. | * |
dc.author.google | Lim K.-M. | * |
dc.author.google | Nam S.-J. | * |
dc.contributor.scopusid | 서은경(7005953758) | * |
dc.contributor.scopusid | 임경민(8916551700) | * |
dc.contributor.scopusid | 남상집(57208839798) | * |
dc.contributor.scopusid | 김민정(56999341200) | * |
dc.date.modifydate | 20240304134025 | * |