Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 박소영 | - |
dc.date.accessioned | 2020-12-07T16:30:08Z | - |
dc.date.available | 2020-12-07T16:30:08Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 0090-3493 | - |
dc.identifier.issn | 1530-0293 | - |
dc.identifier.other | OAK-28135 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/255636 | - |
dc.description.abstract | Objectives: To investigate the impact of normothermia on compliance with sepsis bundles and in-hospital mortality in patients with sepsis who present to emergency departments. Design: Retrospective multicenter observational study. Patients: Nineteen university-affiliated hospitals of the Korean Sepsis Alliance participated in this study. Data were collected regarding patients who visited emergency departments for sepsis during the 1-month period. The patients were divided into three groups based on their body temperature at the time of triage in the emergency department (i.e., hypothermia [< 36 degrees C] vs normothermia [36-38 degrees C] vs hyperthermia [> 38 degrees C]). Interventions: None. Measurements and Main Results: Of 64,021 patients who visited emergency departments, 689 with community-acquired sepsis were analyzed (182 hyperthermic, 420 normothermic, and 87 hypothermic patients). The rate of compliance with the total hour-1 bundle was lowest in the normothermia group (6.0% vs 9.3% in hyperthermia vs 13.8% in hypothermia group;p= 0.032), the rate for lactate measurement was lowest in the normothermia group (62.1% vs 73.1% vs 75.9%;p= 0.005), and the blood culture rate was significantly lower in the normothermia than in the hyperthermia group (p< 0.001). The in-hospital mortality rates in the hyperthermia, normothermia, and hypothermia groups were 8.5%, 20.6%, and 30.8%, respectively (p< 0.001), but there was no significant association between compliance with sepsis bundles and in-hospital mortality. However, in a multivariate analysis, compared with hyperthermia, normothermia was significantly associated with an increased in-hospital mortality (odds ratio, 2.472; 95% CI, 1.005-6.080). This association remained significant even after stratifying patients by median lactate level. Conclusions: Normothermia at emergency department triage was significantly associated with an increased risk of in-hospital mortality and a lower rate of compliance with the sepsis bundle. Despite several limitations, our findings suggest a need for new strategies to improve sepsis outcomes in this group of patients. | - |
dc.language | English | - |
dc.publisher | LIPPINCOTT WILLIAMS & | - |
dc.publisher | WILKINS | - |
dc.subject | emergency department | - |
dc.subject | mortality | - |
dc.subject | normothermia | - |
dc.subject | sepsis bundles | - |
dc.title | Normothermia in Patients With Sepsis Who Present to Emergency Departments Is Associated With Low Compliance With Sepsis Bundles and Increased In-Hospital Mortality Rate* | - |
dc.type | Article | - |
dc.relation.issue | 10 | - |
dc.relation.volume | 48 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 1462 | - |
dc.relation.lastpage | 1470 | - |
dc.relation.journaltitle | CRITICAL CARE MEDICINE | - |
dc.identifier.doi | 10.1097/CCM.0000000000004493 | - |
dc.identifier.wosid | WOS:000573616600038 | - |
dc.author.google | Park, Sunghoon | - |
dc.author.google | Jeon, Kyeongman | - |
dc.author.google | Oh, Dong Kyu | - |
dc.author.google | Choi, Eun Young | - |
dc.author.google | Seong, Gil Myeong | - |
dc.author.google | Heo, Jeongwon | - |
dc.author.google | Chang, Youjin | - |
dc.author.google | Kwack, Won Gun | - |
dc.author.google | Kang, Byung Ju | - |
dc.author.google | Choi, Won-Il | - |
dc.author.google | Kim, Kyung Chan | - |
dc.author.google | Park, So Young | - |
dc.author.google | Shin, Yoon Mi | - |
dc.author.google | Lee, Heung Bum | - |
dc.author.google | Park, So Hee | - |
dc.author.google | Kim, Seok Chan | - |
dc.author.google | Kwak, Sang Hyun | - |
dc.author.google | Cho, Jae Hwa | - |
dc.author.google | Kim, Beongki | - |
dc.author.google | Lim, Chae-Man | - |
dc.contributor.scopusid | 박소영(57219134431) | - |
dc.date.modifydate | 20210915113545 | - |