Photodelivery of β-phenylethylamines

Abstract

We have developed the first photodonors for the trace amino neurotransmitters, β-phenylethylamine (DPSY1) and β-methylphenylethylamine (DPSY2). Our photodonors react rapidly with photosensitized singlet dioxygen (1O2) to yield the amines. The photodelivery of β-phenylethylamine into aqueous solutions by employing liposome scaffolds is successfully demonstrated. This journal is © The Royal Society of Chemistry.