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Blood pool activity on F-18 FDG PET/CT as a possible imaging biomarker of metabolic syndrome
- Title
- Blood pool activity on F-18 FDG PET/CT as a possible imaging biomarker of metabolic syndrome
- Authors
- Bang J.-I.; Moon C.M.; Kim H.O.; Kang S.Y.; Yoon H.-J.; Kim B.S.
- Ewha Authors
- 김범산; 문창모; 윤혜전; 김혜옥; 강서영
- SCOPUS Author ID
- 김범산; 문창모; 윤혜전; 김혜옥; 강서영
- Issue Date
- 2020
- Journal Title
- Scientific Reports
- ISSN
- 2045-2322
- Citation
- Scientific Reports vol. 10, no. 1
- Publisher
- Nature Research
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Association of blood pool (BP) and adipose tissue activity from F-18 fluorodeoxyglucose positron-emission tomography/computed tomography (FDG PET/CT) with the parameters of metabolic syndrome (MetS) and different MetS/obesity types were investigated. 245 subjects underwent FDG PET/CT scan for health check-ups were investigated retrospectively. Associations of BP (BP SUV: SUVmax, SUVmean), visceral (VAT SUV), and subcutaneous adipose tissue (SAT SUV) activity with parameters of MetS, body mass index (BMI), and lipid profiles were analyzed. MetS/obesity types were subdivided into metabolically healthy obese (MHO) and metabolically unhealthy obese (MUO). BP SUV was higher in subjects with MetS (t-test, P < 0.005), and was associated with MetS from multivariable binary logistic regression (OR 5.232 P = 0.010). BP SUV was statistically higher in MUO than in MHO (P < 0.05) along with blood pressure, triglycerides, and HDL-cholesterol. Multivariable binary logistic regression analysis showed MUO had higher blood pressure and BP SUV, while lower HDL-cholesterol relative to MHO after adjusting for triglycerides. © 2020, The Author(s).
- DOI
- 10.1038/s41598-020-74443-9
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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