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Effectiveness of Exercise Intervention in Reducing Body Weight and Glycosylated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus in Korea: A Systematic Review and Meta-Analysis
- Title
- Effectiveness of Exercise Intervention in Reducing Body Weight and Glycosylated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus in Korea: A Systematic Review and Meta-Analysis
- Authors
- Jang, Ji-Eun; Cho, Yongin; Lee, Byung Wan; Shin, Ein-Soon; Lee, Sun Flee
- Ewha Authors
- 이선희
- SCOPUS Author ID
- 이선희
- Issue Date
- 2019
- Journal Title
- DIABETES & METABOLISM JOURNAL
- ISSN
- 2233-6079
2233-6087
- Citation
- DIABETES & METABOLISM JOURNAL vol. 43, no. 3, pp. 302 - 318
- Keywords
- Body weight; Exercise therapy; Glycated hemoglobin A; Meta-analysis; Review
- Publisher
- KOREAN DIABETES ASSOC
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Review
- Abstract
- Background: This study aimed to assess the effectiveness of exercise intervention in reducing body weight and glycosylated hemoglobin (HbA1c) level in patients with type 2 diabetes mellitus (T2DM) in Korea. Methods: Cochrane, PubMed, Embase, KoreaMed, KMbase, NDSL, KCI, RISS, and DBpia databases were used to search randomized controlled trials and controlled clinical trials that compared exercise with non-exercise intervention among patients with non-insulin-treated T2DM in Korea. The effectiveness of exercise intervention was estimated by the mean difference in body weight changes and HbA1c level. Weighted mean difference (WMD) with its corresponding 95% confidence interval (CI) was used as the effect size. The pooled mean differences of outcomes were calculated using a random-effects model. Results: We identified 7,692 studies through literature search and selected 23 articles (723 participants). Compared with the control group, exercise intervention (17 studies) was associated with a significant decline in HbA1c level (WMD, -0.58%; 95% CI, -0.89 to -0.27; I-2=73%). Although no significant effectiveness on body weight was observed, eight aerobic training studies showed a significant reduction in body weight (WMD, -2.25 kg; 95% CI, -4.36 to -0.13; I-2=17%) in the subgroup analysis. Conclusion: Exercise significantly improves glycemic control; however, it does not significantly reduce body weight. Aerobic training can be beneficial for patients with non-insulin-treated T2DM in Korea.
- DOI
- 10.4093/dmj.2018.0062
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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