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dc.contributor.author정성애-
dc.date.accessioned2020-08-13T16:30:13Z-
dc.date.available2020-08-13T16:30:13Z-
dc.date.issued2020-
dc.identifier.issn1976-2283-
dc.identifier.issn2005-1212-
dc.identifier.otherOAK-27237-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/254950-
dc.description.abstractBackground/Alms: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of life (HRQL) among patients newly diagnosed with moderate-to-severe UC who were affiliated with the nationwide prospective cohort study. Methods: Within the first 4 weeks of UC diagnosis, all patients were assessed using the Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Impairment questionnaire, Inflammatory Bowel Disease Questionnaire (IBDQ), and 12-Item Short Form (SF-12) health survey. A multiple linear regression model was used to identify factors associated with HRQL. Results: Between August 2014 and February 2017, 355 patients completed questionnaires. Significant mood disorders requiring psychological interventions, defined by a HADS score >= 11, were identified in 16.7% (anxiety) and 20.6% (depression) of patients. Patients with severe disease were more likely to have presenteeism, loss of work productivity, and activity loss than those with moderate disease (all p<0.05). Significant mood disorders had the strongest negative relationship with total IBDQ score, which indicates disease-specific HRQL (beta coefficient: -22.1 for depression and -40.0 for anxiety, p<0.001). The scores of all SF-12 dimensions, which indicate general HRQL, were remarkably decreased in the study population compared indirectly with previously reported scores in the general population. The Mayo score, C-reactive protein level, and white blood cell count showed significant negative associations with the IBDQ score (p<0.05). Conclusions: Psychosocial screening and timely interventions should be incorporated into the initial care of patients newly diagnosed with UC.-
dc.languageEnglish-
dc.publisherEDITORIAL OFFICE GUT &amp-
dc.publisherLIVER-
dc.subjectColitis-
dc.subjectulcerative-
dc.subjectPatient reported outcome measures-
dc.subjectQuality of life-
dc.subjectAnxiety-
dc.subjectDepression-
dc.titleUnmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea-
dc.typeArticle-
dc.relation.issue4-
dc.relation.volume14-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage459-
dc.relation.lastpage467-
dc.relation.journaltitleGUT AND LIVER-
dc.identifier.doi10.5009/gnl19107-
dc.identifier.wosidWOS:000550767400009-
dc.identifier.scopusid2-s2.0-85078156168-
dc.author.googleMoon, Jung Rock-
dc.author.googleLee, Chang Kyun-
dc.author.googleHong, Sung Noh-
dc.author.googleIm, Jong Pil-
dc.author.googleYe, Byong Duk-
dc.author.googleCha, Jae Myung-
dc.author.googleJung, Sung-Ae-
dc.author.googleLee, Kang-Moon-
dc.author.googlePark, Dong Il-
dc.author.googleJeen, Yoon Tae-
dc.author.googlePark, Young Sook-
dc.author.googleCheon, Jae Hee-
dc.author.googleKim, Hyesung-
dc.author.googleSeo, BoJeong-
dc.author.googleKim, Youngdoe-
dc.author.googleKim, Hyo Jong-
dc.author.googleKASID-
dc.contributor.scopusid정성애(7403676915)-
dc.date.modifydate20200819154515-
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의과대학 > 의학과 > Journal papers
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