View : 257 Download: 0

Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

Title
Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea
Authors
Moon, Jung RockLee, Chang KyunHong, Sung NohIm, Jong PilYe, Byong DukCha, Jae MyungJung, Sung-AeLee, Kang-MoonPark, Dong IlJeen, Yoon TaePark, Young SookCheon, Jae HeeKim, HyesungSeo, BoJeongKim, YoungdoeKim, Hyo JongKASID
Ewha Authors
정성애
SCOPUS Author ID
정성애scopus
Issue Date
2020
Journal Title
GUT AND LIVER
ISSN
1976-2283JCR Link

2005-1212JCR Link
Citation
GUT AND LIVER vol. 14, no. 4, pp. 459 - 467
Keywords
ColitisulcerativePatient reported outcome measuresQuality of lifeAnxietyDepression
Publisher
EDITORIAL OFFICE GUT &

LIVER
Indexed
SCIE; SCOPUS; KCI WOS scopus
Document Type
Article
Abstract
Background/Alms: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of life (HRQL) among patients newly diagnosed with moderate-to-severe UC who were affiliated with the nationwide prospective cohort study. Methods: Within the first 4 weeks of UC diagnosis, all patients were assessed using the Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Impairment questionnaire, Inflammatory Bowel Disease Questionnaire (IBDQ), and 12-Item Short Form (SF-12) health survey. A multiple linear regression model was used to identify factors associated with HRQL. Results: Between August 2014 and February 2017, 355 patients completed questionnaires. Significant mood disorders requiring psychological interventions, defined by a HADS score >= 11, were identified in 16.7% (anxiety) and 20.6% (depression) of patients. Patients with severe disease were more likely to have presenteeism, loss of work productivity, and activity loss than those with moderate disease (all p<0.05). Significant mood disorders had the strongest negative relationship with total IBDQ score, which indicates disease-specific HRQL (beta coefficient: -22.1 for depression and -40.0 for anxiety, p<0.001). The scores of all SF-12 dimensions, which indicate general HRQL, were remarkably decreased in the study population compared indirectly with previously reported scores in the general population. The Mayo score, C-reactive protein level, and white blood cell count showed significant negative associations with the IBDQ score (p<0.05). Conclusions: Psychosocial screening and timely interventions should be incorporated into the initial care of patients newly diagnosed with UC.
Show the fulltext
DOI
10.5009/gnl19107
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE