View : 383 Download: 0

The impact of remission and coexisting migraine on anxiety and depression in cluster headache

Title
The impact of remission and coexisting migraine on anxiety and depression in cluster headache
Authors
Kim, Byung-SuChung, Pil-WookKim, Byung-KunLee, Mi JiPark, Jeong WookChu, Min KyungAhn, Jin-YoungBae, Dae WoongSong, Tae-JinSohn, Jong-HeeOh, KyungmiKim, DaeyoungKim, Jae-MoonKim, Soo-KyoungChoi, Yun-JuChung, Jae MyunMoon, Heui-SooChung, Chin-SangPark, Kwang-YeolCho, Soo-Jin
Ewha Authors
송태진
SCOPUS Author ID
송태진scopus
Issue Date
2020
Journal Title
JOURNAL OF HEADACHE AND PAIN
ISSN
1129-2369JCR Link

1129-2377JCR Link
Citation
JOURNAL OF HEADACHE AND PAIN vol. 21, no. 1
Keywords
AnxietyCluster headacheDepressionHeadacheMigraine
Publisher
BMC
Indexed
SCIE; SCOPUS WOS
Document Type
Article
Abstract
Background Our aim was to investigate the relationship between coexisting cluster headache (CH) and migraine with anxiety and depression during active cluster bouts, and how symptoms change during remission. Methods We analyzed data from 222 consecutive CH patients and 99 age- and sex-matched controls using a prospective multicenter registry. Anxiety or depression was evaluated using the Generalized Anxiety Disorder-7 (GAD-7) or Patient Health Questionnaire-9 (PHQ-9), respectively. Moderate-to-severe anxiety or depression was defined as a score of >= 10 at baseline (during a cluster bout). We assessed for changes in anxiety and depression during CH remission periods. Results Among the CH patients, the prevalence of moderate-to-severe anxiety and depression was seen in 38.2% and 34.6%, respectively. Compared with controls, CH patients were associated with moderate-to-severe anxiety and depression (multivariable-adjusted odds ratio [aOR] = 7.32, 95% confidence intervals [CI] = 3.35-15.99 and aOR = 4.95, 95% CI = 2.32-10.57, respectively). CH patients with migraine were significantly more likely to have moderate-to-severe anxiety and depression (aOR = 32.53, 95% CI = 6.63-159.64 and aOR = 16.88, 95% CI = 4.16-68.38, respectively), compared to controls without migraine. The GAD-7 and PHQ-9 scores were significantly reduced between cluster bout and remission periods (from 6.8 +/- 5.6 to 1.6 +/- 2.8; P < 0.001, and from 6.1 +/- 5.0 to 1.8 +/- 2.4; P < 0.001, respectively). Conclusions Our results indicate that CH patients are at increased risk of anxiety and depression, especially in the presence of coexisting migraine. However, the anxiety and depression can improve during remission periods.
Show the fulltext
DOI
10.1186/s10194-020-01120-7
Appears in Collections:
의료원 > 의료원 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE