Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤주영 | * |
dc.date.accessioned | 2020-04-13T16:30:11Z | - |
dc.date.available | 2020-04-13T16:30:11Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 1433-7851 | * |
dc.identifier.other | OAK-26737 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/253770 | - |
dc.description.abstract | Phototheranostic nanoplatforms are of particular interest for cancer diagnosis and imaging-guided therapy. Herein, we develop a supramolecular approach to fabricate a nanostructured phototheranostic agent through the direct self-assembly of two water-soluble phthalocyanine derivatives, PcS4 and PcN4. The nature of the molecular recognition between PcS4 and PcN4 facilitates the formation of nanostructure (PcS4-PcN4) and consequently enables the fabrication of PcS4-PcN4 with completely quenched fluorescence and reduced singlet oxygen generation, leading to the high photoacoustic and photothermal activity of PcS4-PcN4. In vivo evaluations suggest that PcS4-PcN4 could not only efficiently visualize a tumor with high contrast through whole-body photoacoustic imaging but also enable excellent photothermal therapy for cancer. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim | * |
dc.language | English | * |
dc.publisher | Wiley-VCH Verlag | * |
dc.subject | nanostructures | * |
dc.subject | photoacoustic imaging | * |
dc.subject | photothermal therapy | * |
dc.subject | phthalocyanine | * |
dc.subject | supramolecular chemistry | * |
dc.title | Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy | * |
dc.type | Article | * |
dc.relation.issue | 22 | * |
dc.relation.volume | 59 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 8630 | * |
dc.relation.lastpage | 8634 | * |
dc.relation.journaltitle | Angewandte Chemie - International Edition | * |
dc.identifier.doi | 10.1002/anie.201916147 | * |
dc.identifier.wosid | WOS:000520282000001 | * |
dc.identifier.scopusid | 2-s2.0-85081951611 | * |
dc.author.google | Li X. | * |
dc.author.google | Park E.-Y. | * |
dc.author.google | Kang Y. | * |
dc.author.google | Kwon N. | * |
dc.author.google | Yang M. | * |
dc.author.google | Lee S. | * |
dc.author.google | Kim W.J. | * |
dc.author.google | Kim C. | * |
dc.author.google | Yoon J. | * |
dc.contributor.scopusid | 윤주영(7403587371) | * |
dc.date.modifydate | 20240118162450 | * |