Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최남경 | * |
dc.date.accessioned | 2019-11-19T16:30:33Z | - |
dc.date.available | 2019-11-19T16:30:33Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 1474-0338 | * |
dc.identifier.issn | 1744-764X | * |
dc.identifier.other | OAK-25922 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/251948 | - |
dc.description.abstract | Objective: To determine the association between incident proton pump inhibitor (PPI) use and Clostridium difficile infections across multiple countries Method: National data covering the total population in Australia and Korea, the Canadian population over 65 years and a 3 million person random sample data set from Taiwan were assessed, as were data from a worker insurance population and a hospital inpatient/outpatient population in Japan. Sequence symmetry analysis was used to assess the association with oral vancomycin dispensing as the outcome of interest. Results: 54,957 patients were included. Positive associations were observed in Australia; adjusted sequence ratio (ASR) 2.48 (95% CI 1.90, 3.12), Korea ASR 2.15 (95% CI 2.11, 2.19), Canada ASR 1.45 (95% CI 1.16, 1.79), Japan hospital dataset ASR 3.21 (95% CI 2.12, 4.55) and Japan worker insurance dataset ASR 5.40 (95% CI 2.73, 8.75). The pooled result was ASR 2.40 (95% CI 1.88, 3.05) and 3.16 (95% CI 1.95, 5.10) when limited to Japan, Korean and Taiwan. Results did not vary by individual PPI. The temporal analysis showed effects within the first two weeks of PPI initiation. Conclusion: Our study confirms the association between PPI initiation and C. difficile infections across countries in the Asia-Pacific region. | * |
dc.language | English | * |
dc.publisher | TAYLOR & | * |
dc.publisher | FRANCIS LTD | * |
dc.subject | Proton pump inhibitors | * |
dc.subject | Clostridium difficile | * |
dc.subject | adverse event | * |
dc.subject | Asia | * |
dc.subject | sequence symmetry analysis | * |
dc.title | Proton pump inhibitors and risk of Clostridium difficile infection: a multi-country study using sequence symmetry analysis | * |
dc.type | Review | * |
dc.relation.issue | 12 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1589 | * |
dc.relation.lastpage | 1595 | * |
dc.relation.journaltitle | EXPERT OPINION ON DRUG SAFETY | * |
dc.identifier.doi | 10.1080/14740338.2016.1238071 | * |
dc.identifier.wosid | WOS:000389028600004 | * |
dc.author.google | Roughead, Elizabeth E. | * |
dc.author.google | Chan, Esther W. | * |
dc.author.google | Choi, Nam-Kyong | * |
dc.author.google | Griffiths, Jenna | * |
dc.author.google | Jin, Xue-Mei | * |
dc.author.google | Lee, Joongyub | * |
dc.author.google | Kimura, Michio | * |
dc.author.google | Kimura, Tomomi | * |
dc.author.google | Kubota, Kiyoshi | * |
dc.author.google | Lai, Edward Chia-Cheng | * |
dc.author.google | Man, Kenneth K. C. | * |
dc.author.google | Tuan Anh Nguyen | * |
dc.author.google | Ooba, Nobuhiro | * |
dc.author.google | Park, Byung-Joo | * |
dc.author.google | Sato, Tsugumichi | * |
dc.author.google | Shin, Ju-Young | * |
dc.author.google | Wang, TongTong | * |
dc.author.google | Wong, Ian C. K. | * |
dc.author.google | Yang, Yea-Huei Kao | * |
dc.author.google | Pratt, Nicole L. | * |
dc.contributor.scopusid | 최남경(35486895900) | * |
dc.date.modifydate | 20240304125908 | * |