Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안성복 | * |
dc.date.accessioned | 2019-11-19T16:30:25Z | - |
dc.date.available | 2019-11-19T16:30:25Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0513-5796 | * |
dc.identifier.issn | 1976-2437 | * |
dc.identifier.other | OAK-25959 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/251912 | - |
dc.description.abstract | Purpose: The ratio of serum leptin to adiponectin (L/A ratio) could be used as a marker for insulin resistance. However, few prospective studies have investigated the impact of L/A ratio on improvement of metabolic components in high-risk individuals with metabolic syndrome. We examined the association between L/A ratio and the regression of metabolic syndrome in a population-based longitudinal study. Materials and Methods: A total of 1017 subjects (431 men and 586 women) with metabolic syndrome at baseline (2005-2008) were examined and followed (2008-2011). Baseline serum levels of leptin and adiponectin were analyzed by radioimmunoassay. Area under the receiver operating characteristics curve (AUROC) analyses were used to assess the predictive ability of L/A ratio for the regression of metabolic syndrome. Results: During an average of 2.8 years of follow-up, metabolic syndrome disappeared in 142 men (32.9%) and 196 women (33.4%). After multivariable adjustment, the odds ratios (95% confidence interval) for regression of metabolic syndrome in comparisons of the lowest to the highest tertiles of L/A ratio were 1.84 (1.02-3.31) in men and 2.32 (1.37-3.91) in women. In AUROC analyses, L/A ratio had a greater predictive power than serum adiponectin for the regression of metabolic syndrome in both men (p=0.024) and women (p=0.019). Conclusion: Low L/A ratio is a predictor for the regression of metabolic syndrome. The L/A ratio could be a useful clinical marker for management of high-risk individuals with metabolic syndrome. | * |
dc.language | English | * |
dc.publisher | YONSEI UNIV COLL MEDICINE | * |
dc.subject | Leptin | * |
dc.subject | adiponectin | * |
dc.subject | metabolic syndrome | * |
dc.subject | insulin resistance | * |
dc.subject | prospective study | * |
dc.title | Impact of Serum Leptin to Adiponectin Ratio on Regression of Metabolic Syndrome in High-Risk Individuals: The ARIRANG Study | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 58 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 339 | * |
dc.relation.lastpage | 346 | * |
dc.relation.journaltitle | YONSEI MEDICAL JOURNAL | * |
dc.identifier.doi | 10.3349/ymj.2017.58.2.339 | * |
dc.identifier.wosid | WOS:000401128600011 | * |
dc.author.google | Kang, Dae Ryong | * |
dc.author.google | Yadav, Dhananjay | * |
dc.author.google | Koh, Sang-Baek | * |
dc.author.google | Kim, Jang-Young | * |
dc.author.google | Ahn, Song Vogue | * |
dc.contributor.scopusid | 안성복(47360986600) | * |
dc.date.modifydate | 20240308130443 | * |