Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권영주 | * |
dc.date.accessioned | 2019-10-29T16:30:23Z | - |
dc.date.available | 2019-10-29T16:30:23Z | - |
dc.date.issued | 2019 | * |
dc.identifier.issn | 1359-7345 | * |
dc.identifier.issn | 1364-548X | * |
dc.identifier.other | OAK-25561 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/251635 | - |
dc.description.abstract | 5-Hydroxy-2-phenyl-7-(thiiran-2-ylmethoxy)-4H-chromen-4-one (compound 52) was found as a DNA non-intercalative topo II specific catalytic inhibitor by targeting its ATP-binding domain. Showing changes in interaction with Mg2+, it exhibited highly selective properties against the alpha -isoform with less toxicity, unlike other topo II poisons, such as etoposide. | * |
dc.language | English | * |
dc.publisher | ROYAL SOC CHEMISTRY | * |
dc.title | A chromenone analog as an ATP-competitive, DNA non-intercalative topoisomerase II catalytic inhibitor with preferences toward the alpha isoform | * |
dc.type | Article | * |
dc.relation.issue | 85 | * |
dc.relation.volume | 55 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 12857 | * |
dc.relation.lastpage | 12860 | * |
dc.relation.journaltitle | CHEMICAL COMMUNICATIONS | * |
dc.identifier.doi | 10.1039/c9cc05524j | * |
dc.identifier.wosid | WOS:000495648400022 | * |
dc.identifier.scopusid | 2-s2.0-85073665101 | * |
dc.author.google | Park, Seojeong | * |
dc.author.google | Hwang, Soo-Yeon | * |
dc.author.google | Shin, Jaeho | * |
dc.author.google | Jo, Hyunji | * |
dc.author.google | Na, Younghwa | * |
dc.author.google | Kwon, Youngjoo | * |
dc.contributor.scopusid | 권영주(12446435600) | * |
dc.date.modifydate | 20240422124907 | * |