View : 292 Download: 59

Hemoptysis requiring bronchial artery embolization in patients with nontuberculous mycobacterial lung disease

Title
Hemoptysis requiring bronchial artery embolization in patients with nontuberculous mycobacterial lung disease
Authors
Lee S.H.Lee J.H.Chang J.H.Kim S.J.Yoon H.-Y.Shim S.S.Kim M.U.Choi S.Y.Ryu Y.J.
Ewha Authors
장중현이진화심성신류연주최선영김수정윤희영
SCOPUS Author ID
장중현scopusscopus; 이진화scopus; 심성신scopus; 류연주scopus; 최선영scopusscopus; 김수정scopus
Issue Date
2019
Journal Title
BMC Pulmonary Medicine
ISSN
1471-2466JCR Link
Citation
BMC Pulmonary Medicine vol. 19, no. 1
Keywords
EmbolizationHemoptysisMycobacterium infectionsnontuberculoustherapeuticTuberculosis
Publisher
BioMed Central Ltd.
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Background: Although infections caused by nontuberculous mycobacteria (NTM) are increasing in prevalence, there are few data about hemoptysis in patients with NTM lung disease. This study investigated the characteristics and prognosis of hemoptysis secondary to NTM infection. Methods: Following a retrospective review of cases managed between 2006 and 2016, 183 patients with NTM lung disease were enrolled and analyzed. Results: Among 183 patients with NTM lung disease, Mycobacterium intracellulare (n = 64, 35%) was the major cause of NTM infection, followed by M. avium (n = 59, 32.2%) and M. abscessus complex (n = 40, 21.9%). Hemoptysis developed in 78 patients (42.6%), among whom 33 (42.3%) required bronchial artery embolization (BAE). Between patients with and without hemoptysis, there were no significant differences with respect to sex, radiographic manifestations, distribution over 3 lobes on chest computed tomography, history of pulmonary tuberculosis, antiplatelet or anticoagulation therapy, and species of NTM. However, mean age at diagnosis was significantly lower in the hemoptysis group in univariate and multivariate analyses (65.7 ± 12.8 vs. 59.7 ± 11.8, P = 0.002, odds ratio: 0.969, 95% confidence interval: 0.944-0.996). Among patients with hemoptysis, those requiring medical therapy and those requiring BAE were not significantly different in terms of demographic characteristics, radiographic manifestations, and distribution over 3 lobes. All patients who received BAE showed immediate clinical improvement, no procedure-related complications, and none of them died during the period under review. Conclusions: NTM lung disease patients commonly experienced hemoptysis without specific risk factors except for relatively young age. Although some patients with hemoptysis needed BAE, the success rate of BAE was high, and there were no serious complications associated with BAE. © 2019 The Author(s).
Show the fulltext
DOI
10.1186/s12890-019-0881-z
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
Hemoptysis requiring bronchial artery.pdf(372.58 kB) Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE