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의과대학
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Journal papers
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Adenovirus pneumonia treated with Cidofovir in an immunocompetent high school senior
Title
Adenovirus pneumonia treated with Cidofovir in an immunocompetent high school senior
Authors
Yoon H.-Y.
;
Cho H.-H.
;
Ryu Y.J.
Ewha Authors
류연주
;
조현혜
SCOPUS Author ID
류연주
Issue Date
2019
Journal Title
Respiratory Medicine Case Reports
ISSN
2213-0071
Citation
Respiratory Medicine Case Reports vol. 26, pp. 215 - 218
Keywords
Adenovirus
;
Cidofovir
;
Healthy
;
Immunocompetent
;
Pneumonia
;
Young adult
Publisher
W.B. Saunders Ltd
Indexed
SCOPUS
Document Type
Article
Abstract
Most adenovirus infections are self-limiting in immunocompetent individuals. Here, we report a case of adenovirus pneumonia in a 17-year-old immunocompetent male. He was admitted to our emergency room complaining of a febrile sense, cough, and diarrhea for four days. Crackles in the left lung and a high fever (40.7 °C) were revealed. Initial chest X-ray and computed tomography images showed consolidation in the left lung. We immediately started empirical antibiotic treatment, but his clinical symptoms and pneumonic consolidation in radiography had not improved by hospital day three. Because adenovirus was detected in his sputum using RT-PCR, he was administered Cidofovir. After 24 h of Cidofovir treatment, the symptoms and fever subsided, and the consolidation in his X-ray was significantly reduced by hospital day nine. The early administration of Cidofovir could be beneficial for the treatment of adenovirus infection in immunocompetent patients. © 2019 The Authors
DOI
10.1016/j.rmcr.2019.01.015
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