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Adenovirus pneumonia treated with Cidofovir in an immunocompetent high school senior

Title
Adenovirus pneumonia treated with Cidofovir in an immunocompetent high school senior
Authors
Yoon H.-Y.Cho H.-H.Ryu Y.J.
Ewha Authors
류연주조현혜
SCOPUS Author ID
류연주scopus
Issue Date
2019
Journal Title
Respiratory Medicine Case Reports
ISSN
2213-0071JCR Link
Citation
Respiratory Medicine Case Reports vol. 26, pp. 215 - 218
Keywords
AdenovirusCidofovirHealthyImmunocompetentPneumoniaYoung adult
Publisher
W.B. Saunders Ltd
Indexed
SCOPUS scopus
Document Type
Article
Abstract
Most adenovirus infections are self-limiting in immunocompetent individuals. Here, we report a case of adenovirus pneumonia in a 17-year-old immunocompetent male. He was admitted to our emergency room complaining of a febrile sense, cough, and diarrhea for four days. Crackles in the left lung and a high fever (40.7 °C) were revealed. Initial chest X-ray and computed tomography images showed consolidation in the left lung. We immediately started empirical antibiotic treatment, but his clinical symptoms and pneumonic consolidation in radiography had not improved by hospital day three. Because adenovirus was detected in his sputum using RT-PCR, he was administered Cidofovir. After 24 h of Cidofovir treatment, the symptoms and fever subsided, and the consolidation in his X-ray was significantly reduced by hospital day nine. The early administration of Cidofovir could be beneficial for the treatment of adenovirus infection in immunocompetent patients. © 2019 The Authors
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DOI
10.1016/j.rmcr.2019.01.015
Appears in Collections:
의과대학 > 의학과 > Journal papers
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