Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤주영 | * |
dc.contributor.author | 남상집 | * |
dc.date.accessioned | 2018-12-14T16:30:25Z | - |
dc.date.available | 2018-12-14T16:30:25Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 0003-2700 | * |
dc.identifier.issn | 1520-6882 | * |
dc.identifier.other | OAK-22881 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247578 | - |
dc.description.abstract | In this study, we developed a two-photon fluorescent probe for detection of peroxynitrite (ONOO-) near the N-methyl-D-aspartate (NMDA) receptor. This naphthalimide-based probe contains a boronic acid reactive group and an ifenprodil-like tail, which serves as an NMDA receptor targeting unit. The probe displays high sensitivity and selectivity, along with a fast response time in aqueous solution. More importantly, the probe can be employed along with two-photon fluorescence microscopy to detect endogenous ONOO- near NMDA receptors in neuronal cells as well as in hippocampal tissues. The results suggest that the probe has the potential of serving as a useful imaging tool for studying ONOO- related diseases in the nervous system. | * |
dc.language | English | * |
dc.publisher | AMER CHEMICAL SOC | * |
dc.title | A Two-Photon Fluorescent Probe for Imaging Endogenous ONOO(- )near NMDA Receptors in Neuronal Cells and Hippocampal Tissues | * |
dc.type | Article | * |
dc.relation.issue | 15 | * |
dc.relation.volume | 90 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 9347 | * |
dc.relation.lastpage | 9352 | * |
dc.relation.journaltitle | ANALYTICAL CHEMISTRY | * |
dc.identifier.doi | 10.1021/acs.analchem.8b01960 | * |
dc.identifier.wosid | WOS:000441476600082 | * |
dc.identifier.scopusid | 2-s2.0-85049633526 | * |
dc.author.google | Lee, Dayoung | * |
dc.author.google | Lim, Chang Su | * |
dc.author.google | Ko, Gyeongju | * |
dc.author.google | Kim, Dayoung | * |
dc.author.google | Cho, Myoung Ki | * |
dc.author.google | Nam, Sang-Jip | * |
dc.author.google | Kim, Hwan Myung | * |
dc.author.google | Yoon, Juyoung | * |
dc.contributor.scopusid | 윤주영(7403587371) | * |
dc.contributor.scopusid | 남상집(57208839798) | * |
dc.date.modifydate | 20240220120010 | * |