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A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics

Title
A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics
Authors
Chen L.Wu D.Lim C.S.Kim D.Nam S.-J.Lee W.Kim G.Kim H.M.Yoon J.
Ewha Authors
윤주영남상집
SCOPUS Author ID
윤주영scopus; 남상집scopusscopus
Issue Date
2017
Journal Title
Chemical Communications
ISSN
1359-7345JCR Link
Citation
Chemical Communications vol. 53, no. 35, pp. 4791 - 4794
Publisher
Royal Society of Chemistry
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Hydrogen sulfide (H2S) is a signaling gasotransmitter, which plays various roles in modulating the functions of different systems. In this study, a "turn-on" fluorescent probe for H2S was developed. The probe, whose design is based on a familiar excited state intramolecular proton transfer (ESIPT) fluorophore bearing aggregation-induced emission (AIE) characteristics, was found to exhibit an 80-fold fluorescence enhancement along with a large Stokes shift upon the addition of H2S. Furthermore, the probe was successfully utilized to detect H2S in HeLa cells with both one-photon and two-photon microscopy. This journal is © The Royal Society of Chemistry.
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DOI
10.1039/c7cc01695f
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자연과학대학 > 화학·나노과학전공 > Journal papers
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