Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 백세현 | * |
dc.date.accessioned | 2018-12-07T16:30:17Z | - |
dc.date.available | 2018-12-07T16:30:17Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 2288-6575 | * |
dc.identifier.other | OAK-21587 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/247264 | - |
dc.description.abstract | Purpose: Various methods of sentinel lymph node (SLN) biopsy in thyroid cancer have been introduced. Tc-99m phytate as a radiotracer has been successfully utilized for SLN biopsy in breast, cervix, and endometrial cancer. We assessed the feasibility of SLN dissection using Tc-99m phytate in papillary thyroid carcinoma (PTC). Methods: Seventeen patients with PTC were prospectively enrolled. Ultrasound-guided peritumoral injection of 55.5 MBq Tc-99m phytate in 0.25-mL normal saline was performed. Preoperative single-photon emission-computed tomography (SPECT) and intraoperative gamma-probe were used for SLN detection during operation. Results: Identification rate of SLNs was 70.6% (12 of 17) with SPECT, and 88.2% (15 of 17) with gamma-probe. Combined SPECT and gamma-probe had identification rates of 88.2% (15 of 17). Identification rates of SLNs in central LN compartments were 82.4% (14 of 17) and 41.2% (7 of 17) in lateral LN compartments. Overall sensitivity, specificity, positive predictive value, and negative predictive value of the results of SLN biopsy were 91.6%, 100%, 88.4%, and 100%, respectively. Eight patients (47.1%) had metastasis in SLNs; all patients had SLN metastasis in the central compartment and 2 patients had SLN metastasis in both the central and lateral compartments. Conclusion: Combined SPECT and gamma-probe could detect SLNs with an 88.2% identification rate in PTC. SLN biopsy using Tc-99m phytate is technically feasible. Further investigation is warranted for clinical application of Tc-99m phytate in PTC. [Ann Surg Treat Res 2017;93(5):240-245] Copyright © 2017, the Korean Surgical Society. | * |
dc.language | English | * |
dc.publisher | Korean Surgical Society | * |
dc.subject | Gamma-probe | * |
dc.subject | Papillary thyroid cancer | * |
dc.subject | Phytate | * |
dc.subject | Sentinel lymph node biopsy | * |
dc.subject | Single-photon emissioncomputed tomography | * |
dc.title | Feasibility of sentinel lymph node dissection using Tc-99m phytate in papillary thyroid carcinoma | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 93 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 240 | * |
dc.relation.lastpage | 245 | * |
dc.relation.journaltitle | Annals of Surgical Treatment and Research | * |
dc.identifier.doi | 10.4174/astr.2017.93.5.240 | * |
dc.identifier.wosid | WOS:000415393000002 | * |
dc.identifier.scopusid | 2-s2.0-85038563684 | * |
dc.author.google | Paek S.H. | * |
dc.author.google | Yi K.H. | * |
dc.author.google | Kim S.-J. | * |
dc.author.google | Choi J.Y. | * |
dc.author.google | Lee K.E. | * |
dc.author.google | Park Y.J. | * |
dc.author.google | Park D.-J. | * |
dc.author.google | Kang K.W. | * |
dc.author.google | Chung J.-K. | * |
dc.contributor.scopusid | 백세현(55369850300;57224613040) | * |
dc.date.modifydate | 20240318140539 | * |