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Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis

Title
Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis
Authors
Leutou A.S.Yang I.Le T.C.Hahn D.Lim K.-M.Nam S.-J.Fenical W.
Ewha Authors
임경민남상집
SCOPUS Author ID
임경민scopus; 남상집scopusscopus
Issue Date
2018
Journal Title
Journal of Antibiotics
ISSN
0021-8820JCR Link
Citation
Journal of Antibiotics vol. 71, no. 6, pp. 609 - 612
Publisher
Nature Publishing Group
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria. © 2018 The Author(s) under exclusive licence to the Japan Antibiotics Research Association.
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DOI
10.1038/s41429-018-0033-3
Appears in Collections:
약학대학 > 약학과 > Journal papers
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