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Pitfalls of Frozen Section Diagnosis for Paraganglioma: A Clinicopathologic Analysis and Review of the Literature

Title
Pitfalls of Frozen Section Diagnosis for Paraganglioma: A Clinicopathologic Analysis and Review of the Literature
Authors
Kim, BomiYoo, YoungeunLee, JunghyePark, SanghuiCho, Min-SunSung, Sun HeeKwon, Ghee Young
Ewha Authors
성순희조민선박상희
SCOPUS Author ID
성순희scopus; 조민선scopus; 박상희scopus
Issue Date
2018
Journal Title
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
ISSN
1066-8969JCR Link

1940-2465JCR Link
Citation
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY vol. 26, no. 3, pp. 213 - 220
Keywords
paragangliomafrozen sectionpermanent section
Publisher
SAGE PUBLICATIONS INC
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Review
Abstract
Few paraganglioma (PG) cases include frozen section diagnoses, and therefore, the accuracy of frozen section diagnosis for PG remains unknown. To better understand the histologic characteristics and pitfalls of frozen section findings for PG, 15 PG cases with frozen section diagnoses were selected from 12 articles through PubMed (1984-2015). In addition, we included 3 cases of PG for which intraoperative consultations were requested during a 5-year period (2012-2016) in 2 hospitals. Seven PGs were from the thyroid; 2 from the pancreas; 4 from the mediastinum, retroperitoneum, or mesentery; 1 from the middle ear; and 4 from the urinary bladder (UB). Out of 18 PGs, correct diagnoses were rendered in only 2 cases, and no thyroid or UB PGs were correctly diagnosed on intraoperative consultation. Thyroid PGs were frequently misdiagnosed as medullary thyroid carcinomas (4/7, 57%) and UB PGs were frequently misdiagnosed as malignancies.
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DOI
10.1177/1066896917742199
Appears in Collections:
의과대학 > 의학과 > Journal papers
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