Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서은경 | * |
dc.date.accessioned | 2018-11-16T16:30:21Z | - |
dc.date.available | 2018-11-16T16:30:21Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 0253-6269 | * |
dc.identifier.issn | 1976-3786 | * |
dc.identifier.other | OAK-23417 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/246617 | - |
dc.description.abstract | Two new naphthalenic lactone glycosides, (3S)-9,10-dihydroxy-7-methoxy-3-methyl-1-oxo-3,4-dihydro-1H-benzo[g]isochromene-3-carboxylic acid 9-O-beta-d-glucopyranoside (1) and (3R)-cassialactone 9-O-beta-d-glucopyranoside (2) were isolated from seeds of Cassia obtusifolia Linn., along with five known compounds: (3R)-cassialactone 9-O-beta-d-gentiobioside (3), emodin 1-O-beta-gentiobioside (4), 1-hydroxyl-2-acetyl-3,8-dimethoxy-naphthalene 6-O-beta-d-apiofuranosyl-(1 -> 2)-beta-d-glucopyranoside (5), rubrofusarin 6-O-beta-d-gentiobioside (6), rubrofusarin 6-O-beta-d-triglucoside (7). Structures of 1 and 2 were elucidated by NMR and HR-ESI-MS spectroscopic analysis. Their stereochemistry was determined by CD experiment. All compounds were tested for their ability to inhibit the formation of advanced glycation end-products in vitro. Compounds 1, 2, 3, 5, and 6 showed significant in vitro inhibitory activities (IC50 values of 11.63, 23.40, 7.32, 89.03, and 38.89 A mu M, respectively). | * |
dc.language | English | * |
dc.publisher | PHARMACEUTICAL SOC KOREA | * |
dc.subject | Cassia obtusifolia | * |
dc.subject | Naphthalenic lactone glycosides | * |
dc.subject | Advanced glycation end-products | * |
dc.title | Two new naphthalenic lactone glycosides from Cassia obtusifolia L. seeds | * |
dc.type | Article | * |
dc.relation.issue | 7 | * |
dc.relation.volume | 41 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 737 | * |
dc.relation.lastpage | 742 | * |
dc.relation.journaltitle | ARCHIVES OF PHARMACAL RESEARCH | * |
dc.identifier.doi | 10.1007/s12272-018-1044-0 | * |
dc.identifier.wosid | WOS:000440309800004 | * |
dc.identifier.scopusid | 2-s2.0-85048275803 | * |
dc.author.google | Shrestha, Srijan | * |
dc.author.google | Paudel, Pradeep | * |
dc.author.google | Seong, Su Hui | * |
dc.author.google | Min, Byung Sun | * |
dc.author.google | Seo, Eun Kyoung | * |
dc.author.google | Jung, Hyun Ah | * |
dc.author.google | Choi, Jae Sue | * |
dc.contributor.scopusid | 서은경(7005953758) | * |
dc.date.modifydate | 20240118144717 | * |