View : 424 Download: 101

Enantioselective Synthesis of a Novel Thiazoline Core as a Potent Peroxisome Proliferator-Activated Receptor delta Agonist

Title
Enantioselective Synthesis of a Novel Thiazoline Core as a Potent Peroxisome Proliferator-Activated Receptor delta Agonist
Authors
Lee, Su-JeongSamala, MalleshamWoo, Seo YeonHahn, DongyupKim, DayoungKadayat, Tara ManJung, KyungjinKim, JinaKim, Dong-SuKwon, SugyeongKim, ShinaeKim, Kyung-HeeNam, Sang-JipCho, Sung JinChin, Jungwook
Ewha Authors
남상집
SCOPUS Author ID
남상집scopusscopus
Issue Date
2018
Journal Title
ACS OMEGA
ISSN
2470-1343JCR Link
Citation
ACS OMEGA vol. 3, no. 2, pp. 1970 - 1976
Publisher
AMER CHEMICAL SOC
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
The convergent and enantioselective synthesis of a highly potent human peroxisome proliferator-activated receptor delta agonist is presented. More specifically, the thiazoline structure, which constitutes the biosynthetically distinctive core structure of pulicatin (a secondary metabolite of symbiotic bacteria), was synthesized from a commercially available and inexpensive chiral pool of L-threonine.
Show the fulltext
DOI
10.1021/acsomega.7b01689
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
Files in This Item:
Enantioselective Synthesis.pdf(744.77 kB) Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE