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A case of fulminant bronchiolitis obliterans organizing pneumonia
- A case of fulminant bronchiolitis obliterans organizing pneumonia
- Mi Seon Kim; Jung Hyun Chang; Tai Hee Kim; Ju Hyun Cha; Hae Young Kim; Sung S.-H.
- Ewha Authors
- 성순희; 장중현
- SCOPUS Author ID
- 성순희; 장중현
- Issue Date
- Journal Title
- Tuberculosis and Respiratory Diseases
- Tuberculosis and Respiratory Diseases vol. 45, no. 1, pp. 204 - 212
- Document Type
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- Bronchiolitis obliterans organizing pneumonia (BOOP) is a type of diffuse interstitial lung disease that has emerged in the past decade as an important cause of acute respiratory illness in adult. Clinically, the entity usually starts with a subacute influenza-like illness, followed by cough, progressive dyspnea, and weight loss. Organized inflammatory polypoid materials predominantly affecting distal bronchioles, alveolar ducts, and peribronchial alveolar spaces are a key pathologic findings. BOOP is characterized by a good response to glucocorticoid and an excellent prognosis. However, there is a subset of BOOP who presents with a fulminant course leading to death or chronic severe fibrosis with marked impairment of lung function. Recently, we have experienced a case of rapidly progressive BOOP, diagnosed by open lung biopsy and showed a reluctant response to corticosteroid.
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