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A potential cytotoxic principle of Zingiber cassumunar

Title
A potential cytotoxic principle of Zingiber cassumunar
Authors
Han A.-R.Lee E.-J.Min H.-Y.Kim H.-R.Kook Lee S.Seo E.-K.
Ewha Authors
이상국서은경한아름
SCOPUS Author ID
서은경scopus; 한아름scopus
Issue Date
2003
Journal Title
Natural Product Sciences
ISSN
1226-3907JCR Link
Citation
Natural Product Sciences vol. 9, no. 2, pp. 109 - 111
Indexed
SCOPUS; KCI scopus
Document Type
Article
Abstract
A bioassay-guided fractionation of the active chloroform extracts of the rhizomes of Zingiber cassumunar Roxb. led to the isolation of a potential cytotoxic principle, curcumin (1), along with two inactive compounds, (E)-4-(3′,4′-dimethoxyphenyl)but-3-en-1-ol (2) and (E)-4-(3′,4′-dimethoxyphenyl)but-3-en-1-yl acetate (3). Curcumin (1) showed a significant cytotoxicity against several human cancer cell lines (Col2; 2.30, A549; 12.30, SNU638; IC50 18.80 μg/ml).
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약학대학 > 약학과 > Journal papers
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