DSpace at EWHA: DNA strand-nicking principles of Mucuna birdwoodiana

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DC Field	Value	Language
dc.contributor.author	서은경	*
dc.contributor.author	한아름	*
dc.date.accessioned	2018-06-02T08:14:49Z	-
dc.date.available	2018-06-02T08:14:49Z	-
dc.date.issued	2003	*
dc.identifier.issn	1226-3907	*
dc.identifier.other	OAK-17288	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/244280	-
dc.description.abstract	During our research program to find DNA strand-scission agents from higher plants, the MeOH extracts of the stems of Mucuna birdwoodiana Tutcher. (Leguminosae) exhibited the most potent activity with an IC50 value of 4.9 μg/ml. Thus, detailed laboratory investigation was performed, and led to the isolation of known compounds, (±)-catechin (1) and (-)-epicatechin (2) as active principles. Compounds 1 and 2 showed significant activity of DNA strand-scission with IC50 values of 10.8 and 7.5 μg/ml, respectively (positive control, bleomycin: IC50 3.3 μg/ml).	*
dc.language	English	*
dc.title	DNA strand-nicking principles of Mucuna birdwoodiana	*
dc.type	Article	*
dc.relation.issue	2	*
dc.relation.volume	9	*
dc.relation.index	SCOPUS	*
dc.relation.index	KCI	*
dc.relation.startpage	105	*
dc.relation.lastpage	108	*
dc.relation.journaltitle	Natural Product Sciences	*
dc.identifier.scopusid	2-s2.0-0038503190	*
dc.author.google	Han A.-R.	*
dc.author.google	Mar W.	*
dc.author.google	Seo E.-K.	*
dc.contributor.scopusid	서은경(7005953758)	*
dc.contributor.scopusid	한아름(56278315000;34769874800)	*
dc.date.modifydate	20261006123658	*