A case of primary cutaneous diffuse large B-cell lymphoma

Abstract

Primary cutaneous diffuse large B-cell lymphoma is characterized by a diffuse infiltration of atypical large centroblasts and immunoblasts through the dermis without extracutaneous involvement. We report a case of primary cutaneous diffuse large B-cell lymphoma in a 71-year-old female, who presented with a solitary erythematous nodule on the inner thigh. Physical examination and staging work-up revealed no other extracutaneous or systemic involvement. After radiotherapy, the skin lesion had almost cleared, and no evidence of extracutaneous involvement was observed for 4 months.