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A case of neurotized nevus with sclerotic fibroma-like change

Title
A case of neurotized nevus with sclerotic fibroma-like change
Authors
Jeon H.J.Kim S.H.Whang K.K.Hahm J.H.
Ewha Authors
함정희
Issue Date
2007
Journal Title
Korean Journal of Dermatology
ISSN
0494-4739JCR Link
Citation
Korean Journal of Dermatology vol. 45, no. 10, pp. 1074 - 1077
Indexed
SCOPUS; KCI scopus
Document Type
Article
Abstract
We report a case of neurotized nevus with a sclerotic fibroma-like change in a 60-year-old female patient, who presented with a brown colored pedunculated nodule on the upper quadrant of the abdomen. The skin biopsy revealed a well-circumscribed, non-encapsulated nodule in the reticular dermis, which consisted of hypocellular hyalinized collagen bundles separated by clefts mixed with nevus cells. Nevus cells are small with a spindle appearance and contain Meissner corpuscle-like structures called nevic corpuscles. We suggest that a sclerotic fibroma-like change is an evolutionary end-point of a pre-existing lesion. This is supported further by the fact that neuroid change in the intradermal nevus represents the end stage of maturation of melanocytes of the nevi.
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의과대학 > 의학과 > Journal papers
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