Synthesis of 3′-deoxy-3′-C-hydroxymethyl analogues of tiazofurin and ribavirin

Abstract

On the basis of potent biological activity of 3′-branched-3′- deoxynucleoside analogues, novel ribavirin and tiazofurin derivatives with 3′-C-hydroxymethyl substituent were synthesized, starting from D-xylose. Copyright © Taylor & Francis, Inc.